Settings are often just as important to a story as the tale itself. The Shining had the Overlook. The Legend of Hell House had the Belasco. We fear cabins in the woods and even our own basements. But the mother of all horror settings is the asylum, with a dark pedigree unlike any other.
Humans have always loved to build things, but we occasionally have to make adjustments to our plans. City ordinances, building codes, and property disputes all get in the way. Sometimes, though, the reason we change our plans is much more interesting than that.